Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 179688-27-8, name is Ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate, A new synthetic method of this compound is introduced below., Formula: C15H23NO6
Compound (v) (171.1g), formamidine acetate (79.8 g) was dissolved in n-butanol (1027mL), and nitrogen at elevatedTemperature to 80 C for 5 hours, the reaction was complete by HPLC. Spin dry n-butanol, was added 1711g of isopropyl acetate heated to reflux for 1Hours, cooled to _5 C for 4 hours. Filtered, 50 C and dried under blast (vi) (164.0g), yield 98%, purity>95%. NMR data identified compound (vi) as follows
The synthetic route of 179688-27-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Zhejiang Apeloa Kangyu Pharmaceutical Co.,Ltd; Shanghai Yuyuan Bio-Pharma Co. Ltd; FENG, LICHUN; LI, QIEQIE; (11 pag.)CN103709110; (2016); B;,
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