Adding a certain compound to certain chemical reactions, such as: 3399-21-1, name is cis-Dimethyl cyclohexane-1,4-dicarboxylate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3399-21-1, Application In Synthesis of cis-Dimethyl cyclohexane-1,4-dicarboxylate
REFERENCE EXAMPLE 6 Monomethyl cis-1,4-cyclohexanedicarboxylate In 35 ml of methanol was dissolved 3.46 g of dimethyl cis-1,4-cyclohexanedicarboxylate, and 17.3 ml of 1N aqueous sodium hydroxide solution was added thereto, and the resulting mixture was stirred at room temperature for 1.5 hours. The solvent was distilled off under reduced pressure and the obtained aqueous solution was washed with ethyl acetate. The pH of the mixture was adjusted to 1 with diluted hydrochloric acid under ice-cooling and the mixture was extracted with ethyl acetate. The extracts were washed with an aqueous sodium chloride solution and dried over anhydrous magnesium sulfate. The solvent was distilled off under reduced pressure to obtain a colorless crystalline solid. Isopropyl ether was added to the crystalline solid and the crystalline solid was collected by filtration to obtain 1.76 g of the desired compound as a pale yellow crystalline solid. m.p.: 91-93 C.; NMR spectrum (CDCl3 +d6 -DMSO) delta ppm: 1.60-2.00(8H,m), 2.42-2.52(2H,m), 3.67(3H,s)
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it.
Reference:
Patent; Sankyo Company, Limited; US5843973; (1998); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics