Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2216-92-4, name is N-Phenylglycine Ethyl Ester, A new synthetic method of this compound is introduced below., category: esters-buliding-blocks
To a solution of 1 (1.0 eq.) in dioxane at room temperature were added the appropriate alpha-amino ethyl ester (1.0 eq.) and DIEA (1.2 eq.). The mixture was stirred at room temperature for 24 hours. The solvent was removed under vacuum. The residue was purified on a silica gel column to give 28.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; KEMIA, INC.; WO2006/91737; (2006); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics