Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 33993-24-7, name is Cyclopropanecarboxylic anhydride, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 33993-24-7
Step 1 : To a solution of methyl 2-isocyanoacetate (72.7 g, 729 mmol) and DBU (1 1 1 g, 729 mmol) in THF (1 L) was added a solution of cyclopropanecarboxylic anhydride (112 g, 729 mmol) in THF (100 mL) portionwise at 5C. The mixture was stirred at rt overnight, concentrated and purified by flash chromatography (PE/EtOAc = 5:1 ) to afford methyl 5-cyclopropyloxazole-4- carboxylate lnt-1 a-11. 1H-NMR (CDCI3, 300 MHz): delta 1.04-1.18 (m, 4H), 2.74-2.79 (m, 1 H), 3.91 (s, 3H), 7.60 (s, 1 H)
According to the analysis of related databases, 33993-24-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GILEAD SCIENCES, INC.; KINZEL, Olaf; KREMOSER, Claus; SCHMITT, Aaron C.; GEGE, Christian; (205 pag.)WO2016/96115; (2016); A1;,
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