Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 111-61-5, name is Ethyl stearate, A new synthetic method of this compound is introduced below., Formula: C20H40O2
General procedure: To a solution of 100 mg of compound 3 (55 mumol, 1 equiv) in 2 ml of corresponding fatty ester (excess), 100 mg of Lipozyme was added. The reaction was set under rotary evaporator at 50 C during 8 to 14 hours depending on the corresponding fatty ester. Lipozyme was filtered, and the solution was purified directly on silica gel (from pure EtOAc to EtOAc/MeOH 4:1(v/v)), giving white solid. Yields: 4 (80mg): 74%, 5 (75mg): 68%, 6 (72mg): 64%, 7 (69mg): 60%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Article; Miao, Yong; Djedani-Pilard, Florence; Bonnet, Vronique; Beilstein Journal of Organic Chemistry; vol. 10; (2014); p. 2654 – 2657;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics