Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 2475-80-1, name is Methyl 2-amino-5-methoxybenzoate, A new synthetic method of this compound is introduced below., Safety of Methyl 2-amino-5-methoxybenzoate
The MicroKans were washed once with DCE prior to addition of reagents. A solution of 1,3-diisopropylcarbodiimide (0.1 M) and 1-hydroxy-7-azabenzotriazole (0.2 M) in NMP (0.75 mL/MicroKan) was prepared. The solution was added to the MicroKans in a round bottom flask, and the mixture was degassed. The round bottom flask was put on a shaker for two hours. Then methyl 2-amino-5-methoxybenzoate (0.4 M) was added. The flask was heated to 70 C. for 48 hours, and the MicroKans were washed with DMF (3×), 8:1:1 THF/H2O/AcOH (2×), and THF (3×) to afford 9D-1.
The synthetic route of 2475-80-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Kick, Ellen K.; Lawrence, R. Michael; Fink, Brian E.; Misra, Raj N.; Vite, Gregory D.; US2006/135619; (2006); A1;,
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