Sources of common compounds: 13195-64-7

Adding a certain compound to certain chemical reactions, such as: 13195-64-7, name is Diisopropyl malonate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13195-64-7, name: Diisopropyl malonate

Adding a certain compound to certain chemical reactions, such as: 13195-64-7, name is Diisopropyl malonate, belongs to esters-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 13195-64-7, name: Diisopropyl malonate

(1) Using 830 mmol of sodium hydride as a catalyst,200 mmol of diisopropyl malonate with440 mmol of propargyl bromide was added to the column210 mL of anhydrous acetonitrile in ice water bath,Stirring reaction for 8 hours,The product was washed with water,Extracted with ethyl acetate,Decompression spin dry,getBrownyellowSolid product,I.e. Compound 1;

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Diisopropyl malonate, and friends who are interested can also refer to it.

Reference:
Patent; Anhui Normal University; Hu Yimin; Xu Xiaoliang; (20 pag.)CN106866639; (2017); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics