Discovery of 426-65-3

Statistics shows that 426-65-3 is playing an increasingly important role. we look forward to future research findings about Ethyl Pentafluoropropionate.

426-65-3, name is Ethyl Pentafluoropropionate, belongs to esters-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 426-65-3

P-xylene (30 mL) of ethyl 2,2,3,3,3-pentafluoropropanoate (S-1) (7.69 g, 40.0 mmol)1,3-diaminopropan-2-ol (S-2) (3.61 g, 40.0 mmol) was added to the solution, and the mixture was stirred at 160 C. for 4 hours.The solvent was distilled off under reduced pressure,Compound (S-3) (yield: 10.1 g)As a yellow oil.

Statistics shows that 426-65-3 is playing an increasingly important role. we look forward to future research findings about Ethyl Pentafluoropropionate.

Reference:
Patent; Kaken Pharmaceutical Co., Ltd.; Watanabe, Atsushi; Sato, Yuki; ogura, Keiji Tamada; Tatsumi, Yoshiyuki; (283 pag.)JP2018/145180; (2018); A;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics