A facile approach to trans-4,5-pyrrolidine lactam and application in the synthesis of nemonapride and streptopyrrolidine was written by Huang, Wei;Ma, Jing-Yi;Yuan, Mu;Xu, Long-Fei;Wei, Bang-Guo. And the article was included in Tetrahedron in 2011.Recommanded Product: (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate This article mentions the following:
An efficient approach to trans-4-hydroxylpyrrolidine lactams, e.g. I [R1 = t-Bu, PhCH2; R2 = H, Me; Me2CH, etc.; R3 = H, TBSO], starting from an amino acid is described. The utility of this method has been demonstrated in the synthesis of antipsychotic nemonapride and antiangiogenic streptopyrrolidine. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9Recommanded Product: (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate).
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics