Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3618-04-0, name is trans-Ethyl 4-hydroxycyclohexanecarboxylate, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C9H16O3
Compound 300.1. Ethyl 4-methoxycyclohexanecarboxylate. Into a 100-mL round- bottom flask, was placed a solution of ethyl 4-hydroxycyclohexane-l-carboxylate (1 g, 5.81 mmol) in tetrahydrofuran (20 mL). Sodium hydride (349 mg, 8.72 mmol, 60percent) was added to the reaction at 0 ¡ãC in portions, then stirred for 20 min. This was followed by the addition of CH3I (865 mu, 11.6 mmol) at 0 ¡ãC. The reaction mixture was stirred overnight at room temperature, quenched with 6 mL of brine and extracted with 3 x 40 mL of ether. The combined organic layers were washed with 2 x 20 mL of brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 800 mg (74percent) of the title compound as a colorless oil.
According to the analysis of related databases, 3618-04-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; 3-V BIOSCIENCES, INC.; HEUER, Timothy Sean; OSLOB, Johan D.; MCDOWELL, Robert S.; JOHNSON, Russell; YANG, Hanbiao; EVANCHIK, Marc; ZAHARIA, Cristiana A.; CAI, Haiying; HU, Lily W.; WO2015/95767; (2015); A1;,
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