Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation was written by Jiang, Wenhao;Zhao, Qing;Tang, Wenjun. And the article was included in Chinese Journal of Chemistry in 2018.Application In Synthesis of Ethyl 3-oxo-3-(m-tolyl)propanoate This article mentions the following:
Five structurally novel P-chiral bis(benzooxaphosphole) ligands (BABIBOPs) are developed, providing high efficiency for the 1st time in Pd-catalyzed asym. hydrogenation of 灏?aryl and 灏?alkyl substituted 灏?keto esters. With a palladium BABIBOP catalyst, chiral 灏?hydroxyl carboxylic esters are formed in excellent enantioselectivities (up to>99% ee) and yields at catalyst loading as low as 0.01 mol%. In the experiment, the researchers used many compounds, for example, Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9Application In Synthesis of Ethyl 3-oxo-3-(m-tolyl)propanoate).
Ethyl 3-oxo-3-(m-tolyl)propanoate (cas: 33166-79-9) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application In Synthesis of Ethyl 3-oxo-3-(m-tolyl)propanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics