Library Synthesis Using 5,6,7,8-Tetrahydro-1,6-naphthyridines as Scaffolds was written by Zhou, Ya;Beeler, Aaron B.;Cho, Sanghyun;Wang, Yuehong;Franzblau, Scott G.;Snyder, John K.. And the article was included in Journal of Combinatorial Chemistry in 2008.Related Products of 16413-26-6 This article mentions the following:
The chem. of 5,6,7,8-tetrahydro-1,6-naphthyridine scaffolds I [R = H, R1 = Me, R2 = Ph, CH2OPh, n-Bu; R1 = Ph, R2 = 2-Me-4-MeOC6H3], synthesized by intramol. cobalt-catalyzed [2 + 2 + 2] cyclizations, has been exploited for library synthesis. Urea, amide, and sulfonamide formations were used in the synthesis of a 101-membered library. Screening of the library for antituberculosis activity revealed three lead compds I [R = (R)-PhCH(Me)NHCO, 4-MeOC6H4NHCO, 4-NCC6H4SO2, R1 = Ph, R2 = 2-Me-4-MeOC6H3]. In the experiment, the researchers used many compounds, for example, 3-Cyanophenylisocyanate (cas: 16413-26-6Related Products of 16413-26-6).
3-Cyanophenylisocyanate (cas: 16413-26-6) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Related Products of 16413-26-6
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics