Cu-Catalyzed Aminodifluoroalkylation of Alkynes and α-Bromodifluoroacetamides was written by Lv, Yunhe;Pu, Weiya;Chen, Qian;Wang, Qingqing;Niu, Jiejie;Zhang, Qian. And the article was included in Journal of Organic Chemistry in 2017.Application of 185619-66-3 This article mentions the following:
The copper-catalyzed highly regioselective aminodifluoroalkylation of alkynes and α-bromodifluoroacetamides was realized for the first time. With this method, 3,3-difluoro-1H-pyrrol-2(3H)-ones were constructed in a single step from various alkynes and α-bromodifluoroacetamides substrates without using any extra oxidant. In the experiment, the researchers used many compounds, for example, tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3Application of 185619-66-3).
tert-Butyl (3-ethynylphenyl)carbamate (cas: 185619-66-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 185619-66-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics