Propellanes. Part LXXXII. Preparation and labeling of [20.3.3]propellane-24,27-dione was written by Ashkenazi, Pnina;Kettenring, Juergen;Migdal, Shmuel;Gutman, Arie L.;Ginsburg, David. And the article was included in Helvetica Chimica Acta in 1985.SDS of cas: 3903-40-0 This article mentions the following:
The title compound I was prepared by Kolbe’s electrochem. reaction of MeO2C(CH2)10CO2H to give MeO2C(CH2)20CO2Me which was treated with Na and Me3SiCl in PhMe, and then aqueous HCl-THF to give 89% the hydroxy ketone II (R = OH, R1 = H). Treatment of II with Bi2O3 in AcOH gave 77% the diketone II (RR1 = O) which was treated with MeO2CCH2COCH2CO2Me and KOH in MeOH-C6H6 for 10 days, followed by 6N HCl to give 83.3% I. Treatment of I with D2O and HCl in a sealed tube at 120° achieved more than 90% incorporation of 2H at the positions α to the carbonyls. However, similar treatment of I with tritiated water achieved only 3% 3H-incorporation. In the experiment, the researchers used many compounds, for example, 12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0SDS of cas: 3903-40-0).
12-Methoxy-12-oxododecanoic acid (cas: 3903-40-0) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 3903-40-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics