Zhang, Xiang-Jin published the artcileCascade Wolff Rearrangement/Acylation: A Metal-Free and Eco-Friendly Approach for 4-Hydroxy-pyrazolo[3,4-b]pyridin-6-ones and N-Pyrazole Amides Synthesis from 5-Aminopyrazoles and α-Diazoketones, HPLC of Formula: 30414-53-0, the publication is Journal of Organic Chemistry (2021), 86(23), 17471-17481, database is CAplus and MEDLINE.
A highly chemoselective cascade Wolff rearrangement/acylation reaction between 5-aminopyrazoles and diazo compounds has been developed. The protocol can facilitate the switchable synthesis of 4-hydroxy-pyrazolo[3,4-b]pyridin-6-ones I (R1 = Me, Et, Ph, etc.; R2 = Ph, t-Bu, 2-naphthyl, etc.; R3 = Ph, 4-MeOC6H4, 3-thienyl, etc.) and N-pyrazole amides II (R1 = Me, t-Bu, Ph; R2 = Ph, 4-FC6H4, 2-naphthyl, etc.; R3 = Me, c-hexyl, Ph, etc.; R4 = Me, Et) with the merits of a broad substrate scope, high functional group compatibility, and green and sustainable performance manner. All reactions proceeded efficiently without any catalyst and additives (acid and base) and resulted in the release of benign N2, wherein di-Et carbonate served as a green benign solvent.
Journal of Organic Chemistry published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C12H9N3O4, HPLC of Formula: 30414-53-0.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics