Whitmore, Frank C. published the artcileAction of primary Grignard reagents on tert-butylacetyl chloride. II, Computed Properties of 5340-78-3, the publication is Journal of the American Chemical Society (1938), 2790-2, database is CAplus.
Addition of EtMgBr to tert-BuCH2COCl gives tert-BuCH2CO2Et(I), 77% of neopentylethylcarbinyl tert-butylacetate, 51% of Et neopentyl ketone and some tert-BuCH2CO2H (II). PrMgBr gives I, II, 36.7% of Pr neopentyl ketone, 20% of neopentylpropylcarbinyl tert-butylacetate and dodecenes. BuMgBr gives I, 34% of Bu neopentyl ketone, 23% of neopentylbutylcarbinyl tert-butylacetate and some tetradecenes. AmMgBr gives I, II, 29% of Am neopentyl ketone, 21% of neopentylamylcarbinyl tert-butylacetate. In no experiment was neopentyl carbinol or its tert-butylacetate found. The above yields are nearly the same as those obtained by adding the acid chloride to an excess of the Grignard reagent. Neopentyl chloride (0.8 mol.), through the Mg derivative, gives with HCHO 0.47 mol. of neopentylcarbinol, b739 140-6°; this with tert-BuCH2COCl gives 57% of neopentylcarbinyl tert-butylacetate, b26 104°. tert-BuCH2CO2H and EtOH with concentrated H2SO4 gives 77% of Et tert-butylacetate, b740 102°.
Journal of the American Chemical Society published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C10H10O3, Computed Properties of 5340-78-3.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics