Seki, Toshimi published the artcileStudies on agents with vasodilator and β-blocking activities. III. Synthesis and activity of optical isomers of TZC-1370, Recommanded Product: (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Chemical & Pharmaceutical Bulletin (1995), 43(10), 1719-23, database is CAplus and MEDLINE.
Optical isomers of TZC-1370 were prepared from (R)- and (S)-1-(2-chlorophenoxy)-2,3-epoxypropane. When given i.v. to anesthetized rats, the (S)-isomer was about 40 times more potent in terms of β-blocking activity than the (R)-isomer, while their hypotensive activities were equipotent with that of the racemic compound, TZC-1370.
Chemical & Pharmaceutical Bulletin published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C15H12O6, Recommanded Product: (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics