Aviram, Adina published the artcileEffect of the cytostatic butyric acid pro-drug, pivaloyloxymethyl butyrate, on the tumorigenicity of cancer cells, Recommanded Product: (Pivaloyloxy)methyl butyrate, the publication is Journal of Cancer Research and Clinical Oncology (1997), 123(5), 267-271, database is CAplus and MEDLINE.
Pivaloyloxymethyl butyrate (AN-9) was demonstrated to be a cytostatic but not cytotoxic agent in a myelomonocytic cell line (WEHI). The expression of the early regulatory genes, c-myc and c-jun were changed. Although these events occurred already after 1 h of exposure to AN-9, the tumorigenicity of these reduced only after 4 h of exposure. Tumorigenicity of the highly metastatic subclone of Lewis lung carcinoma was almost diminished after 1h of exposure. In both cell types a 10-fold higher concentration of BA did not affect the tumorigenicity of the cells as did AN-9.
Journal of Cancer Research and Clinical Oncology published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Recommanded Product: (Pivaloyloxy)methyl butyrate.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics