Liu, Chengwei published the artcileHighly-chemoselective step-down reduction of carboxylic acids to aromatic hydrocarbons via palladium catalysis, COA of Formula: C9H8O4, the publication is Chemical Science (2019), 10(22), 5736-5742, database is CAplus and MEDLINE.
The highly selective method for the direct step-down reduction of carboxylic acids RCOOH (biphenyl-4-yl, 1-naphthyl, 1-methyl-1H-indole-3-yl, etc.) to arenes RH, proceeding via well-defined Pd(0)/(II) catalytic cycle was described. The method shows a remarkably broad substrate scope, enabling to direct the classical acyl reduction towards selective decarbonylation by a redox-neutral mechanism. The utility of this reaction is highlighted in the direct defunctionalization of pharmaceuticals and natural products, and further emphasized in a range of traceless processes using removable carboxylic acids under mild, redox-neutral conditions orthogonal to protodecarboxylation. Extensive DFT computations were conducted to demonstrate preferred selectivity for the reversible oxidative addition and indicated that a versatile hydrogen atom transfer (HAT) pathway is operable.
Chemical Science published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, COA of Formula: C9H8O4.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics