Geesi, Mohammed H. published the artcileMetal-doped TiO2 nanocatalysts in an MX2/urea mixture for the synthesis of benzothiazoles bearing substituted pyrrolidin-2-ones: enhanced catalytic performance and antibacterial activity, SDS of cas: 617-52-7, the publication is Journal of Environmental Chemical Engineering (2021), 9(4), 105344, database is CAplus.
Pyrrolidinone derivatives I (R = Ph, 2-MeC6H4, 4-HOC6H4, 3-Cl-4-FC6H3, etc.) were synthesized by reacting various arylamines RNH2 with di-Me itaconate using water as the solvent in a microwave. The obtained pyrrolidinone derivatives I were further reacted with 2-aminothiophenol under microwave irradiation with the assistance of a deep eutectic mixture (CuCl2 or NiCl2/urea) and Cu- or Ni-doped TiO2 nanoparticles to afford the final derivatives II incorporating both pyrrolidin-2-one and benzothiazole rings. To determine the optimum reaction conditions, the effects of temperature, solvent nature, and reaction time were investigated. Under the optimal operation conditions, high reaction yields were achieved. The developed strategy exhibited advantages of a short reaction time, eco-friendliness, and high productivity. Finally, the obtained derivatives II were examined in terms of their antibacterial potential against selected Gram-neg. and Gram-pos. bacterial strains: all the derivatives II, except for II (R = 4-MeOC6H4), exhibited activity against the tested bacteria.
Journal of Environmental Chemical Engineering published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, SDS of cas: 617-52-7.
Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics