Hossain, Jamal Md. published the artcileRepurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress, HPLC of Formula: 55981-09-4, the main research area is review public health crisis palliative care repurposing strategy pandemic; SARS covid clin trial review; SARS-CoV-2; clinical trials; covid-19 pandemic; palliative care; public health crisis; repurposing strategy.
The pathogenic and highly transmissible etiol. agent, SARS-CoV-2, has caused a serious threat COVID-19 pandemic. WHO has declared the epidemic a public health emergency of international concern owing to its high contagiosity, mortality rate, and morbidity. Till now, there is no approved vaccine or drug to combat the COVID-19 and avert this global crisis. Areas covered In this narrative review, we summarized the updated results (Jan. to August 2020) of the most promising repurposing therapeutic candidates to treat the SARS-CoV-2 viral infection. The repurposed drugs classified under four headlines like antivirals, anti-parasitic, immune-modulating, and miscellaneous drugs were discussed with their in vitro efficacy to recent clin. advancements against COVID-19. Expert opinion Currently, palliative care, ranging from outpatient management to intensive care, including oxygen administration, ventilator support, i.v. fluids therapy, with some repurposed drugs, are the primary weapons to fight against COVID-19. Until a safe and effective vaccine is developed, an evidence-based drug repurposing strategy might be the wisest option to save people from this catastrophe. Several existing drugs are now under clin. trials, and some of them are approved in different places of the world for emergency use or as adjuvant therapy in COVID-19 with standard of care.
Expert Review of Anti-Infective Therapy published new progress about Antiviral agents. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, HPLC of Formula: 55981-09-4.
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