Zhu, Chen published the artcileTowards nanoparticles with site-specific degradability by ring-opening copolymerization induced self-assembly in organic medium, COA of Formula: C16H30O2, the main research area is nanoparticle degradability ring opening copolymerization self assembly organic medium.
Reversible addition-fragmentation chain transfer (RAFT)-mediated radical ring-opening copolymerization-induced self-assembly (rROPISA) in heptane at 15 weight% solids was successfully applied to the copolymerization of benzyl methacrylate (BzMA) with 2-methylene-1,3-dioxepane (MDO) from a poly(lauryl methacrylate) (PLMA) macro-RAFT agent. Despite less efficient control of the copolymerization compared to similar copolymerization with 2-methylene-4-phenyl-1,3-dioxolane (MPDL) or 5,6-benzo-2-methylene-1,3-dioxepane (BMDO), it yielded stable, diblock copolymer nanospheres (Dz = 100-200 nm) containing tunable amounts of polycaprolactone (PCL)-like degradable units in the core (FMDO = 0.04-0.19), resulting in significant degradation under accelerated hydrolytic conditions. Synthesis of surface-degradable diblock copolymer nanoparticles was then performed through the synthesis of P(LMA-co-BMDO) and P(LMA-co-MPDL) macro-chain transfer agents (CTAs). Even though partial livingness during chain extension with BzMA by PISA was noticed, stable nanospheres were obtained for FBMDO = 0.05 and porous nanospheres for FBMDO = 0.08-0.09, whose average diameters increased with the BMDO content. Attempts to prepare “”all-degradable”” vinyl particles were also made by rROPISA of BzMA and BMDO (or MPDL) from degradable macro-CTAs showing degradation in agreement with the copolymers’ expected structure.
Polymer Chemistry published new progress about Chain transfer agents. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, COA of Formula: C16H30O2.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics