TFAA-H3PO4 mediated rapid and single-step synthesis of mutual prodrugs of paracetamol and NSAIDs was written by Kankanala, Kavitha;Billur, Ramya;Reddy, Vangala Ranga;Mukkanti, Khagga;Pal, Sarbani. And the article was included in Green Chemistry Letters and Reviews in 2012.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:
A clean and operationally simple method was developed for the preparation of mutual prodrugs using paracetamol and various nonsteroidal anti-inflammatory drugs. The methodol. involves use of trifluoroacetic anhydride/H3PO4 in acetonitrile and a variety of mutual prodrugs was prepared in good yields by this single-step C-O bond forming reaction. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 5003-48-5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics