Simoni, Daniele et al. published their research in Drug Design and Discovery in 1992 | CAS: 37905-02-5

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C12H18O3

New isoxazole derivatives of retinoids: synthesis and activity on growth and differentiation of tumor cells was written by Simoni, Daniele;Manfredini, Stefano;Tabrizi, Mojgan Aghazadeh;Bazzanini, Rita;Baraldi, Pier G.;Ferroni, Roberto;Traniello, Francesca;Nastruzzi, Claudio;Feriotto, Giordana;Gambari, Roberto. And the article was included in Drug Design and Discovery in 1992.Electric Literature of C12H18O3 The following contents are mentioned in the article:

The effects of several newly synthesized isoxazole analogs of retinoids on differentiation and proliferation of in vitro culture tumor cell lines are reported. Some of the tested compounds exhibit significant differentiating action, inducing adipogenic conversion of the Chinese hamster FH06T1-1 cell line in a range of 2-10 times the activity of retinoic acid and retinol. In addition, most of the compound tested display antiproliferative activity comparable to that of natural retinoids. The reported data could be of interest for exptl. anticancer therapy. This study involved multiple reactions and reactants, such as (2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5Electric Literature of C12H18O3).

(2E,6E)-3,7-Dimethyl-8-oxoocta-2,6-dien-1-yl acetate (cas: 37905-02-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C12H18O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics