Determination of two components and their related substances in pediatric benorilate and vitamin B1 granules by HPLC was written by Lu, Xia;Hu, Mingtong;Yu, Xu. And the article was included in Zhongguo Yiyao Gongye Zazhi in 2015.Synthetic Route of C17H15NO5 The following contents are mentioned in the article:
A HPLC method was established for the determination of benorilate and vitamin B1, and their related substances, paracetamol, aspirin and salicylic acid, in pediatric benorilate and vitamin B1 granules. A Kromasil ODS-1 column was used with the mobile phase of methanol: 0.2 mol/L acetic acid/sodium acetate buffer (pH 4.8) by gradient elution, at the detection wavelength of 245 nm. It was linear for benorilate and vitamin B1 in the concentration ranges of 0.2-2.0 mg/mL and 10-100 μg/mL. Their average recoveries were 100.2% and 99.6%, with RSDs of 0.62% and 1.27%, resp. The LLODs of paracetamol, aspirin and salicylic acid were 0.026, 0.048 and 0.048 μg/mL, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Synthetic Route of C17H15NO5).
4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Synthetic Route of C17H15NO5
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics