Preparation of Mono- and Diisocyanates in Flow from Renewable Carboxylic Acids was written by Phung Hai, Thien An;De Backer, Laurent J. S.;Cosford, Nicholas D. P.;Burkart, Michael D.. And the article was included in Organic Process Research & Development in 2020.Reference of 106-73-0 The following contents are mentioned in the article:
Diisocyanates used in polyurethanes are commonly prepared by phosgenation of petroleum-sourced diamines. This involves highly toxic phosgene and produces corrosive HCl, limiting synthetic applications. In our search for a renewable source for diisocyanates, we have developed a practical methodol. for the production of isocyanates from algae-biomass-derived fatty acids or other renewable sources. This technique utilizes flow chem. to prepare and convert high-energy intermediates, thus mitigating safety concerns. By the use of continuous flow, acyl azides are prepared from hydrazides and subsequently heated to undergo Curtius rearrangement, affording isocyanates in one scalable process. The method is efficient, safe, and sustainable, offers an opportunity to prepare isocyanates and diisocyanates from renewable feedstocks, and is amenable to distributed manufacturing processes. This study involved multiple reactions and reactants, such as Methyl heptanoate (cas: 106-73-0Reference of 106-73-0).
Methyl heptanoate (cas: 106-73-0) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 106-73-0
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics