Synthesis and Evaluation of Partly Fluorinated Block Copolymers as MRI Imaging Agents was written by Peng, Hui;Blakey, Idriss;Dargaville, Bronwin;Rasoul, Firas;Rose, Stephen;Whittaker, Andrew K.. And the article was included in Biomacromolecules in 2009.HPLC of Formula: 3063-94-3 The following contents are mentioned in the article:
A series of well-defined diblock copolymers of acrylic acid with partially fluorinated acrylate and methacrylate monomers were synthesized using ATRP as potential 19F MRI imaging agents. The diblock copolymers could undergo spontaneous self-assembly in mixed and aqueous solvents to form stable micelles with a diameter from approx. 20-45 nm, having a fluorine-rich core that provides a strong signal for MRI examinations The observed MRI image intensities were related to the NMR longitudinal and transverse relaxation times, and were found to depend on polymer structure and method of micellization. Two distinct T2 relaxation times were measured; on comparison of expected MRI image intensities with those observed exptl., methacrylate polymers show systematically lower signal intensity than acrylate polymers. This is related to the presence of a population of nuclear spins having short T2 relaxation times that cannot be detected under high-resolution NMR and MRI conditions. This study involved multiple reactions and reactants, such as 1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3HPLC of Formula: 3063-94-3).
1,1,1,3,3,3-Hexafluoroisopropylmethacrylate (cas: 3063-94-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 3063-94-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics