Ishida, Hideharu’s team published research in Carbohydrate Research in 302 | CAS: 10378-06-0

Carbohydrate Research published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, HPLC of Formula: 10378-06-0.

Ishida, Hideharu published the artcileSynthetic studies on sialoglycoconjugates. 94. Synthesis of 6′-GM2, a regioisomer of ganglioside GM2, for studying the mechanism of action of GM2 activator, HPLC of Formula: 10378-06-0, the publication is Carbohydrate Research (1997), 302(3-4), 223-227, database is CAplus and MEDLINE.

GM2 activator is a protein cofactor that assists β-hexosaminidase (HexA) in hydrolyzing the β-linked N-acetylgalactosamine (GalNAc) in ganglioside GM2. We report a synthesis of the regioisomer of ganglioside GM2, 6′-GM2, in which the GalNAc residue is linked, not to the 4-OH, but to the 6-OH of Gal to show that the resistance of GalNAc in GM2 to HexA is due to the specific structure of the GM2-epitope, β-D-GalNAc-(1→4)-α-Neu5Ac-(2→3)-β-D-Gal→.

Carbohydrate Research published new progress about 10378-06-0. 10378-06-0 belongs to esters-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Ester,Inhibitor,Inhibitor, name is (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]oxazole-6,7-diyl diacetate, and the molecular formula is C14H19NO8, HPLC of Formula: 10378-06-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics