Fe3O4/ZnO/MWCNTs magnetic nanocomposites promoted synthesis of new chromeno pyrano [2,3-d]thiazins: Investigation of antioxidant and antibacterial activities was written by Dadashi, Hani;Hajinasiri, Rahimeh;Hossaini, Zinatossadat. And the article was included in Applied Organometallic Chemistry in 2021.Formula: C4H7NS The following contents are mentioned in the article:
The Fe3O4/ZnO/MWCNTs magnetic nanocomposites as a high-performance organometallic catalyst were employed for the preparation of new chromeno pyrano [2,3-d]thiazins derivatives I (R = Me, OMe, NO2; R1 = H, Me; R2 = CH3, C2H5, C6H5, 4-CH3C6H4, 4-CH3OC6H4, 4-O2NC6H4; R3 = CH(CH3)2, C2H5, C6H5, 4-CH3C6H4, 4-CH3OC6H4, 4-O2NC6H4; X = O, NH) in high yields via the five component reactions of 2-hydroxyacetophenones like 1-(2-Hydroxy-3-methyl-5-nitrophenyl)ethanone, 1-(2-Hydroxy-5-methylphenyl)ethan-1-one, 1-(2-Hydroxy-3,5-dimethylphenyl)ethanone and 1-(2-hydroxy-5-methoxyphenyl)ethanone, di-Me carbonate, aldehydes R2CHO, malononitrile or Et 2-cyanoacetate, and isothiocyanates R3NCS in ionic liquid at room temperature The Fe3O4/ZnO/MWCNTs MNCs were synthesized using ionic liquid [OMIM]Br as a stabilizer and soft template. As well Fe3O4/ZnO/MWCNTs MNCs show a good improvement in the yield of the product and showed significant reusable ability. Due to having NH group in synthesized compounds, antioxidant property of some synthesized compounds I was investigated by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment Furthermore, the disk diffusion test on Gram-pos. and Gram-neg. bacteria is utilized for investigation of antimicrobial activity of some chromeno pyrano [2,3-d]thiazins I. The achieved outcomes of this experiment demonstrate that these synthesized compounds I could prevent growth of bacteria. Short time of reaction, high yields of product, easy separation of catalyst, and products are some benefits of this process. This study involved multiple reactions and reactants, such as Isopropylisothiocyanate (cas: 2253-73-8Formula: C4H7NS).
Isopropylisothiocyanate (cas: 2253-73-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C4H7NS
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics