Quality Control of Methyl 4-fluoro-3-nitrobenzoateIn 2018 ,《Metal-Free Synthesis of Pyrrolo[1,2-a]quinoxalines Mediated by TEMPO Oxoammonium Salts》 appeared in Synthesis. The author of the article were Huo, Heng-rui; Tang, Xiang-Ying; Gong, Yue-fa. The article conveys some information:
We herein describe a novel TEMPO oxoammonium salt initiated Pictet-Spengler reaction of imines, generated in situ from carbonyl compounds and pyrrole- or indole-containing substrates, to afford 4,5-dihydropyrrolo[1,2- a]quinoxalines or 5,6-dihydroindolo[1,2- a]quinoxalines in good to excellent yields. Moreover, a one-pot synthesis of a biol. important quinoxaline is achieved via a cyclization-dehydrogenation process using one equivalent of the oxoammonium salt. The experimental process involved the reaction of Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9Quality Control of Methyl 4-fluoro-3-nitrobenzoate)
Methyl 4-fluoro-3-nitrobenzoate(cas: 329-59-9) belongs to methyl benzoate. Methyl benzoate reacts at both the ring and the ester, depending on the substrate. Electrophiles attack the ring, illustrated by acid-catalysed nitration with nitric acid to give methyl 3-nitrobenzoate.Quality Control of Methyl 4-fluoro-3-nitrobenzoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics