《Stereospecific Electrophilic Fluorocyclization of α,Β-Unsaturated Amides with Selectfluor》 was written by Fei, Haiyang; Xu, Zheyuan; Wu, Hongmiao; Zhu, Lin; Jalani, Hitesh B.; Li, Guigen; Fu, Yao; Lu, Hongjian. SDS of cas: 609-14-3 And the article was included in Organic Letters in 2020. The article conveys some information:
An efficient fluorocyclization of α,Β-unsaturated amides I (R = Ph, 4-methoxyphenyl, 4-nitrophenyl, i-Pr, n-Bu, Bn; R1 = H, Me, Et, Ph, n-Pr, cyclopropyl, 4-methylphenyl, 4-nitrophenyl; R2 = H, Me, Et, Ph, octyl, etc.; R3 = H, Me, Et, Ph, n-Pr, cyclohexyl, etc.; R4 = Me, Et, i-Pr, t-Bu) through a formal halocyclization process is developed. The reaction proceeds under transition-metal-free conditions and leads to the formation of fluorinated oxazolidine-2,4-diones II with excellent regio- and diastereoselectivity. The evaluation of the reaction mechanism based on preliminary experiments and d. functional theory calculations suggests that a synergetic syn-oxo-fluorination occurs and is followed by an anti-oxo substitution reaction. The reaction opens a new window in the field of stereospecific fluorofunctionalization. After reading the article, we found that the author used Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3SDS of cas: 609-14-3)
Ethyl 2-methyl-3-oxobutanoate(cas: 609-14-3) belongs to ketone compounds. They are most widely used as solvents, especially in industries manufacturing explosives, lacquers, paints, and textiles. Ketones are also used in tanning, as preservatives, and in hydraulic fluids.SDS of cas: 609-14-3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics