In 2022,Guan, Zhipeng; Zhong, Xingxing; Ye, Yayu; Li, Xiangwei; Cong, Hengjiang; Yi, Hong; Zhang, Heng; Huang, Zhiliang; Lei, Aiwen published an article in Chemical Science. The title of the article was 《Selective radical cascade (4+2) annulation with olefins towards the synthesis of chroman derivatives via organo-photoredox catalysis》.Reference of Benzyl acrylate The author mentioned the following in the article:
Here a new (4 + 2) radical annulation approach for the construction of these functional six-membered frameworks I (R = ethoxycarbonyl, N-methyl-N-phenylcarbamoyl, benzenesulfonyl, (2,2,6,6-tetramethylpiperidin-1-yl)carbonyl, etc.; R1 = H, Me, methoxycarbonyl; R2 = H, Me, OMe; R3 = H, F, Ph, 2,2-dichlorocyclopropyl, etc.; R2R3 = -CH=CH-CH=CH-; R4 = H, Me, OMe, CF3; R5 = H, Me;) via photocatalysis was reported. Featuring mild reaction conditions, the protocol allows readily available N-hydroxyphthalimide esters II and electron-deficient olefins RCH=CHR1 to be converted into a wide range of valuable chromans I in a highly selective manner. Moreover, the present strategy can be used in the late-stage functionalization of natural product derivatives and biol. active compounds, which demonstrated the potential application. This method is complementary to the traditional Diels-Alder [4 + 2] cycloaddition reaction of ortho-quinone methides II and electron-rich dienophiles, since electron-deficient dienophiles were smoothly transformed into the desired chromans I. After reading the article, we found that the author used Benzyl acrylate(cas: 2495-35-4Reference of Benzyl acrylate)
Benzyl acrylate(cas: 2495-35-4) has been used in preparation of high refractive index polyacrylates. Benzyl acrylate is used in the preparation of heptanoic acid benzyl ester. It is used to prepare polybenzylacrylate using azobisisobutyronitrile as initiator.Reference of Benzyl acrylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics