In 2004,Stanforth, Stephen P.; Tarbit, Brian; Watson, Michael D. published ãSynthesis of pyridine and 2,2′-bipyridine derivatives from the aza-Diels-Alder reaction of substituted 1,2,4-triazinesã?Tetrahedron published the findings.Recommanded Product: 16982-21-1 The information in the text is summarized as follows:
Amidrazone and tricarbonyl derivatives reacted in the presence of 2,5-norbornadiene to give pyridines, e.g., I. When the reaction was carried out in the presence of 2,3-dihydrofuran, the corresponding lactones were obtained. The 2,2′-bipyridine derivatives were similarly obtained in good yields from the reaction of amidrazone and tricarbonyl derivatives the presence of 2,5-norbornadiene.Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1Recommanded Product: 16982-21-1) was used in this study.
Ethyl 2-amino-2-thioxoacetate(cas: 16982-21-1) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Recommanded Product: 16982-21-1
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics