On November 5, 2021, Nugent, Jeremy; Sterling, Alistair J.; Frank, Nils; Mousseau, James J.; Anderson, Edward A. published an article.Recommanded Product: 10472-24-9 The title of the article was Synthesis of α-quaternary bicyclo[1.1.1]pentanes through synergistic organophotoredox and hydrogen atom transfer catalysis. And the article contained the following:
Bicyclo[1.1.1]pentanes (BCPs) are of importance in drug design as sp3-rich bioisosteres of arenes and tert-Bu groups, however the preparation of BCPs with adjacent quaternary carbons is barely known. Authors report a facile synthesis of α-quaternary BCPs using organophotoredox and hydrogen atom transfer catalysis in which α-keto radicals, generated through oxidation of β-ketocarbonyls, underwent efficient addition to [1.1.1]propellane. The BCP products can be transformed into a variety of useful derivatives including enantioenriched BCPs featuring α-quaternary stereocenters. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Recommanded Product: 10472-24-9
The Article related to quaternary bicyclopentane preparation, ketoester ketoamide diketone ketonitrile synergistic organophotoredox hydrogen atom transfer, General Organic Chemistry: Synthetic Methods and other aspects.Recommanded Product: 10472-24-9
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Ester – an overview | ScienceDirect Topics