van Dongen, Stijn F. M.; Maiuri, Paolo; Marie, Emmanuelle; Tribet, Christophe; Piel, Matthieu published an article in 2013, the title of the article was Triggering Cell Adhesion, Migration or Shape Change with a Dynamic Surface Coating.Category: esters-buliding-blocks And the article contains the following content:
The authors here report a strategy for study of cell dynamics that involves only azido-(PLL-g-PEG) (APP) and the addition of a reactive BCN-RGD peptide to the cell culture medium as a trigger. APP and BCN-RGD allow the noninvasive ‘switching on’ of cell adhesion with very high contrast, because the adhesion mol. is only introduced when desired, leaving the ‘switched off’ surface featureless. To demonstrate the versatility of this approach, the authors show a set of experiments that validate the trigger. Then, the authors combine it with patterned surfaces. Patterns allow for interesting applications where cell adhesion is triggered while cells are already attached to certain areas of the substrate (in situ triggering). As typical applications, the authors show the induction of both single and collective cell migration, create cocultures, and trigger the synchronous control of cell shape change, illustrating dynamic control. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Category: esters-buliding-blocks
The Article related to cell adhesion migration shape dynamic surface coating, Biochemical Methods: Culture and Preservation and other aspects.Category: esters-buliding-blocks
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