On May 1, 2013, Zhang, Junjie; Wang, Huanxia; Ma, Yun; Wang, Youming; Zhou, Zhenghong; Tang, Chuchi published an article.Application In Synthesis of (R)-Methyl 3-hydroxybutanoate The title of the article was CaF2 catalyzed SN2 type chlorodehydroxylation of chiral secondary alcohols with thionyl chloride: a practical and convenient approach for the preparation of optically active chloroalkanes. And the article contained the following:
A CaF2 catalyzed chlorodehydroxylation of chiral secondary alcs. with thionyl chloride has been developed. The chlorination reaction is effective for a wide range of alcs., generating the corresponding chloroalkanes in good yield with high optical purity with inversion of the original configuration of the alc. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Application In Synthesis of (R)-Methyl 3-hydroxybutanoate
The Article related to chloroalkane chiral preparation, calcium fluoride catalyst chlorodehydroxylation chiral secondary alc thionyl chloride, Aliphatic Compounds: Halides and Halonium Compounds and other aspects.Application In Synthesis of (R)-Methyl 3-hydroxybutanoate
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