Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 103-09-3, Name is 2-Ethylhexyl acetate, molecular formula is C10H20O2, belongs to esters-buliding-blocks compound, is a common compound. In a patnet, author is Wheatley, Emilie, once mentioned the new application about 103-09-3, Category: esters-buliding-blocks.
Diastereo-, Enantio-, and anti-Selective Formation of Secondary Alcohol and Quaternary Carbon Stereocenters by Cu-Catalyzed Additions of B-Substituted Allyl Nucleophiles to Carbonyls
A general method for the synthesis of secondary homoallylic alcohols containing alpha-quaternary carbon stereogenic centers in high diastereo- and enantioselectivity (up to >20:1 dr and >99:1 er) is disclosed. Transformations employ readily accessible aldehydes, allylic diboronates, and a chiral copper catalyst and proceed by gamma-addition of in situ generated enantioenriched boron-stabilized allylic copper nucleo-philes. The catalytic protocol is general for a wide variety of aldehydes as well as a variety of 1,1-allylic diboronic esters. Hammett studies disclose that diastereoselectivity of the reaction is correlated to the electronic nature of the aldehyde, with dr increasing as aldehydes become more electron poor.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 103-09-3. The above is the message from the blog manager. Category: esters-buliding-blocks.