On September 7, 2000, Davies, John S.; Enjalbal, Christine; Nguyen, Corrine; Al-Jamri, Loai; Naumer, Christian published an article.Quality Control of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate The title of the article was The synthesis and properties of Gla- and Phe-containing analogs of cyclic RGD pentapeptides. And the article contained the following:
Cyclopentapeptides containing the Arg-Gly-Asp (RGD) motif have been synthesized using solid-phase assembly of side-chain-protected linear precursors, followed by solution-phase cyclization. The replacement of the Asp residue by γ-carboxyglutamic acid (Gla) is a novel feature which gives rise to an analog which inhibits cell adhesion, yet its congeners do not show activity in binding assays with recombinant integrin receptors. NMR techniques support a β/γ-turn conformation in most of the analogs. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).Quality Control of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
The Article related to rgd cyclopentapeptide analog carboxyglutamate containing synthesis conformation, cell adhesion assay carboxyglutamate containing cyclopentapeptide analog rgd, Amino Acids, Peptides, and Proteins: Poly(Amino Acids) and Peptides and other aspects.Quality Control of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate
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