Gu, Jian; Cai, Chun published an article in 2016, the title of the article was Synthesis of substituted indolizines via radical oxidative decarboxylative annulation of 2-(pyridin-2-yl)acetate derivatives with α,β-unsaturated carboxylic acids.Quality Control of Ethyl indolizine-1-carboxylate And the article contains the following content:
A copper mediated radical oxidative annulation of 2-(pyridin-2-yl)acetate derivatives I (R = CO2Me, CO2Et, CO2i-Pr, CO2t-Bu, CN) with α,β-unsaturated carboxylic acids R1CH=CHCOOH (R1 = H, C6H5, 4-ClC6H4, 2-thienyl, etc.) is developed. This study offers a new and expedient strategy for the synthesis of useful indolizines II in moderate to good yields and exhibits a broad substrate scope and good functional group tolerance. The experimental process involved the reaction of Ethyl indolizine-1-carboxylate(cas: 93476-46-1).Quality Control of Ethyl indolizine-1-carboxylate
The Article related to indolizine preparation, unsaturated carboxylic acid pyridine oxidative decarboxylative annulation copper catalyst, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Quality Control of Ethyl indolizine-1-carboxylate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics