On October 15, 2021, Wu, Yinrong; Wen, Kangmei; Chen, Jiewen; Shi, Jie; Yao, Xingang; Tang, Xiaodong published an article.Name: Methyl 2-cyclopentanonecarboxylate The title of the article was Copper-Mediated Decarboxylative Coupling between Arylacetic Acids and 1,3-Dicarbonyl Compounds. And the article contained the following:
A copper-mediated decarboxylative coupling reaction between arylacetic acids and 1,3-dicarbonyl compounds was described for the synthesis of ((indolyl)methyl)-oxocycloalkyl-esters, e.g., I. Significantly, methanocycloocta[b]indoles II [R = COOEt, CONHEt, SO2Ph, etc.; R1 = H, 4-Cl, 5-Br, etc.] were also obtained by sequential intramol. dehydrocyclization process in some cases. This protocol featured a broad substrate scope, simple operations, and good yields. Moreover, the products exhibited potent antiproliferative activity against the human cancer cell lines by a MTT assay. The experimental process involved the reaction of Methyl 2-cyclopentanonecarboxylate(cas: 10472-24-9).Name: Methyl 2-cyclopentanonecarboxylate
The Article related to indolyl methyl oxocycloalkyl ester preparation antitumor, arylacetic acid dicarbonyl compound decarboxylative coupling copper mediated, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Name: Methyl 2-cyclopentanonecarboxylate
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