On February 5, 1986, Iwasaki, Genji; Saeki, Seitaro; Hamana, Masatomo published an article.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate The title of the article was A novel nucleophilic substitution of the formyl group in p-nitrobenzaldehyde with some carbanions. And the article contained the following:
p-O2NC6H4CHO (I) reacted with some active methylene compounds in the presence of a strong base at low temperatures to give p-substituted nitrobenzenes by a 2-step course involving the initial formation of the aldol adducts and the subsequent displacement of the carbinol moieties with excess carbanions. p-O2NC6H4CHROH were formed preferentially from RH (R = CHMeCOPh, CHMeCOEt, CH2CO2CMe3) or exclusively from RH [R = CMe2, COCHMe2, CH(CN)2]. Thus, I was added to MeCOPr in Me3COK in liquid NH3 at -70° to give 85% p-O2NC6H4CH2COPr. The experimental process involved the reaction of tert-Butyl 2-(4-nitrophenyl)acetate(cas: 29704-38-9).Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate
The Article related to nucleophile substitution nitrobenzaldehyde carbanion, formyl group substitution carbanion, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Aldehydes and Derivatives, Including Sulfur Analogs and other aspects.Quality Control of tert-Butyl 2-(4-nitrophenyl)acetate
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