Romero, Eugenie; Minard, Corinne; Benchekroun, Mohamed; Ventre, Sandrine; Retailleau, Pascal; Dodd, Robert H.; Cariou, Kevin published an article in 2017, the title of the article was Base-Mediated Generation of Ketenimines from Ynamides: Direct Access to Azetidinimines by an Imino-Staudinger Synthesis.Formula: C12H14F3NO2 And the article contains the following content:
Ynamides were used as precursors for the in situ generation of highly reactive ketenimines that could be trapped with imines in a [2+2] cycloaddition This imino-Staudinger synthesis led to a variety of imino-analogs of β-lactams, namely azetidinimines I [Ar1 = Ph, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-IC6H4, 4-F3CC6H4; Ar2 = Ph, 4-MeOC6H4, 4-ClC6H4, 4-BrC6H4, 4-IC6H4, 4-MeO2CC6H4, 4-t-Bu-O2CC6H4; Ar3 = Ph, 4-MeOC6H4] that could be further functionalized through a broad range of transformations. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Formula: C12H14F3NO2
The Article related to azetidinimine preparation, ketenimine insitu generation ynamide imine imino staudinger cycloaddition, staudinger synthesis, [2+2] cycloaddition, azetidinimines, ketenimines, ynamides and other aspects.Formula: C12H14F3NO2
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