On September 7, 2012, Grove, Charles I.; Di Maso, Michael J.; Jaipuri, Firoz A.; Kim, Michelle B.; Shaw, Jared T. published an article.Safety of (R)-Methyl 3-hydroxybutanoate The title of the article was Synthesis of 6,6′-Binaphthopyran-2-one Natural Products: Pigmentosin A, Talaroderxines A and B. And the article contained the following:
Efficient and stereoselective syntheses of pigmentosin A I, talaroderxine A II, and its diastereomer talaroderxine B III are reported. The binaphthyl ring system is assembled by vanadium-catalyzed phenolic coupling of tricyclic precursors. These key intermediates were prepared by Michael-Dieckmann annulation of a protected orsellinate ester, with the requisite pyranones accessed by a new variant of Ghosez’s sulfone-epoxide annulation. Preliminary biol. experiments are reported for pigmentosin. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Safety of (R)-Methyl 3-hydroxybutanoate
The Article related to pigmentosin a stereoselective synthesis coupling vanadium catalyst, michael dieckmann annulation stereoselective synthesis pigmentosin a talaroderxine, talaroderxine a b stereoselective synthesis coupling vanadium catalyst and other aspects.Safety of (R)-Methyl 3-hydroxybutanoate
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics