Boyles, David C.; Curran, Timothy T.; Greene, Derek; Macikenas, Dainius; Parlett, Roger V. published the artcile< Novel, base-promoted reaction of N-alkoxycarbonyl-O-(halo-substituted 4-nitrophenyl)hydroxylamines>, Synthetic Route of 112-63-0, the main research area is alkoxycarbonyl hydroxyaniline preparation; nitrophenyl alkoxycarbonyl hydroxylamine base reaction.
The base-promoted reactions of N-alkoxycarbonyl-O-(nitrophenyl)hydroxylamines which contain a halogen attached to the aromatic ring were described. The reaction is promoted under mild conditions (NaHCO3 or K2CO3) and provides N-alkoxycarbonyl-N-hydroxyaniline. In a crossover experiment, some scrambling was observed which suggests that the reaction is inter- and intramol. in nature. N-Boc-(2,6-dichloro-4-nitrophenyl)hydroxylamine was also found to N-Boc aminate Bn2NH to form the protected hydrazine in modest yield. For example, treatment of (2,6-dichloro-4-nitrophenoxy)carbamic acid 1,1-dimethylethyl ester with sodium hydrogen carbonate gave an N-hydroxyaniline derivative, i.e., (2,6-dichloro-4-nitrophenyl)hydroxycarbamic acid 1,1-dimethylethyl ester (I). Further reaction of I with N-(phenylmethyl)benzenemethanamine gave 2,2-bis(phenylmethyl)hydrazinecarboxylic acid 1,1-dimethylethyl ester.
Tetrahedron Letters published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics