Kisel, V. M.; Potikha, L. M.; Kovtunenko, V. A. published the artcile< Condensed isoquinolines. Part 9. Alkylation of 7,12-dihydro-5H-isoquino[2,3-a]quinazolin-5-ones>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is isoquinoquinazolinone benzyl halide alkylation; spiroisoquinoquinazolinindane preparation; diazadibenzopleiadene preparation.
The alkylation of 7,12-dihydro-5H-isoquino[2,3-a]quinazolin-5-one proceeds at N(6) or C(7) depending on the type of alkylating agent and reaction conditions. C(7)-alkylation occurs in the presence of base. The secondary alkylation of the 7-alkyl derivatives occurs at the same position under these conditions. Depending on the conditions, the reaction with ortho-xylylene dibromide leads to spiro[5H-isoquino-[2,3-a]quinazolin-7(12H),2′-indane]-5-one or 11-oxo-4b,5,10,16-tetrahydro-11H-10a-azonia-15b-azadibenzo[a,e]pleiadene bromide.
Chemistry of Heterocyclic Compounds (New York)(Translation of Khimiya Geterotsiklicheskikh Soedinenii) published new progress about Alkylation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics