Arribas, Andres; Calvelo, Martin; Fernandez, David F.; Rodrigues, Catarina A. B.; Mascarenas, Jose L.; Lopez, Fernando published the artcile< Highly Enantioselective Iridium(I)-Catalyzed Hydrocarbonation of Alkenes: A Versatile Approach to Heterocyclic Systems Bearing Quaternary Stereocenters>, Quality Control of 623-50-7 , the main research area is alkenyl azaheterocycle iridium phosphine catalyst enantioselective regioselective hydrocarbonation; fused polycyclic azaheterocycle preparation; C-H activation; enantioselective; heterocycles; hydrocarbonation; iridium.
A versatile, highly enantioselective intramol. hydrocarbonation reaction that provides a direct access to heteropolycyclic systems bearing chiral quaternary carbon stereocenters was reported. The method, which relies on an iridium(I)/bisphosphine chiral catalyst, was particularly efficient for the synthesis of five-, six- and seven-membered fused indole and pyrrole products, bearing one and two stereocenters, with enantiomeric excesses of up to >99%. DFT computational studies allowed to obtain a detailed mechanistic profile and identify a cluster of weak non-covalent interactions as key factors to control the enantioselectivity.
Angewandte Chemie, International Edition published new progress about Amides Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 623-50-7 belongs to class esters-buliding-blocks, and the molecular formula is C4H8O3, Quality Control of 623-50-7 .
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics