In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 581065-95-4 as follows. Recommanded Product: 581065-95-4
N-Fmoc imino diacetic acid, PSMA11 , (107 mg, 0.30 mmol) was treated with PSMA12 (212 mg, 0.66 mmol), TBTU (193 mg, 0.60 mmol), HOBt (92 mg, 0.60 mmol), and DIEA (209 muIota_, 1.20 mmol) in DMF for 2 h. The reaction was concentrated in vacuo and purified through Si02 gel chromatography to afford PSMA13 (250 mg, 91 %). AP-ESI+ Mass calcd C49H75N3016: 961.51 , Found: 962.6 [M+H]+, 984.6 [M+Na]+
According to the analysis of related databases, 581065-95-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SOLSTICE BIOLOGICS, LTD.; BRADSHAW, Curt, W.; ELTEPU, Laxman; KABAKIBI, Ayman; LAM, Son; LIU, Bin; LIU, Dingguo; MEADE, Bryan, R.; SAKAMURI, Sukumar; WO2015/69932; (2015); A1;,
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