Yue, Bin; Wang, Yangang; Zhang, Chunxia; Ding, Yunlong; Liu, Zhipeng published the artcile< Efficacy of Shaobei injection in the treatment of grade II-III hemorrhoids and the effect on fibulin protein expression: A study protocol of a randomized controlled trial>, Category: esters-buliding-blocks, the main research area is Shaobei injection hemorrhoid fibulin protein expression.
Hemorrhoids are a common and seriously disruptive condition that seriously affects people’s lives in terms of treatment. Injection therapy is an effective minimally invasive scheme for the treatment of grade II-III hemorrhoids, but its clin. application is limited by the adverse reactions caused by injection drugs. Some clin. studies have confirmed the efficacy and safety of Shaobei injection as a traditional Chinese medicine extract However, there is no standard randomized controlled study to verify its efficacy and explore its potential mechanism. This is a prospective, randomized, single blind, parallel controlled trial to study the efficacy of Shaobei injection in the treatment of grade II-III hemorrhoids and its effect on the expression of fibulin-3 and fibulin-5 in fibulin protein family. The patients will be randomly divided into a treatment group and control group. The treatment group will be treated with Shaobei injection, and the control group will be treated with rubber band ligation. The observation indexes include: visual anal. scale, postoperative hospital stay, total use of painkillers, fibulin-3 and fibulin-5, hemorrhoids recurrence, and adverse events. Finally, the data will be statistically analyzed by SPASS 18.0 software. This study will compare the efficacy ofShaobei injection with the rubber band ligation method in the treatment of grade II-III hemorrhoids and investigate its effect on the expression of fibulin-3 and fibulin-5 in the fibulin protein family. The results of this study will provide a basis for the clin. use of Paeoniflora injection as an alternative to traditional sclerosing agent in the treatment of grade II-III hemorrhoids.
Medicine (Philadelphia, PA, United States) published new progress about Analgesics. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.
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