Christoffers, Jens; Rossler, Ulrich published the artcile< One-pot generation and conversion of trichloroacetimidates for the racemization-free allylation and benzylation of α-hydroxyesters and the enantiopure synthesis of a chiral diglycole>, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate, the main research area is trichloroacetamidate generation benzylation allylation hydroxy ester; diglycole chiral preparation.
O-Allylations and O-benzylations of the α-hydroxy esters (S)-Et lactate and mandelate and di-Me maleate are performed without racemization. The reagents applied, O-allyl- and O-benzyltrichloroacetimidates ROC(CCl3):NH (R = PhCH2, allyl), are prepared and converted in a one-pot procedure. After protection by benzylation, (S)-(-)-Et lactate is converted by a sequence of carbonyl reduction, alc. activation, ether formation, and deprotection to the optically active diglycole (S,S)-(+)-Bis(2-hydroxypropyl) ether.
Journal fuer Praktische Chemie (Weinheim, Germany) published new progress about Allylation. 617-55-0 belongs to class esters-buliding-blocks, and the molecular formula is C6H10O5, Recommanded Product: (S)-Dimethyl 2-hydroxysuccinate.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics