Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Quality Control of 87-13-8.
Thopate, Yogesh;Singh, Richa;Rastogi, Sumit K.;Sinha, Arun K. research published 《 Cascade Multicomponent Reaction Involving Unprecedented Gould Jacobs-Heck/Suzuki Coupling-Hydrolysis-Decarboxylation Reactions in One Pot: Rapid Synthesis of Hybrid Heterocyclic Molecules》, the research content is summarized as follows. Multicomponent one-pot five-step reactions by combining two known name reactions viz. Gould-Jacobs reaction and Heck reaction for the synthesis of stilbene/biaryl-quinolone hybrid mols. I [R = H, F; R1 = Ph, 4-MeC6H4, 4-ClC6H4, etc.], while Gould-Jacobs reaction and Suzuki reaction for II [R2 = Ph, 4-OMeC6H4, 4-FC6H4, 3-ClC6H4] from readily available 4-iodoanilines, (diethyl-2-(ethoxymethylene)malonate) and styrenes/aryl boronic acids was reported. The use of di-Ph ether as a reaction solvent effectively mediated not only the Gould-Jacobs reaction but surprisingly also the Heck reaction for the first time. Further, di-Ph ether also allowed easy isolation of crude product due to polar nature of the product via precipitation The developed protocol thus offered unprecedented synthesis of hybrid mols. by converging five steps (Gould-Jacobs reaction, Heck or Suzuki cross coupling, hydrolysis and decarboxylation) into one pot with simultaneous generation of C-C and C-N bonds besides cleavage of C-O and C-C bonds.
Quality Control of 87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.
Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., 87-13-8.
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics